rs28938472
A SNP in the GSS gene on chromosome 20. Its most notable genotype is C;T: Carrier of a glutathione synthetase deficiency mutation
- Gene
- GSS
- Location
- Chr 2034,936,976 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- 23andMe, AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in clinvar
- C;TMost notableBadCarrier of a glutathione synthetase deficiency mutation
SNPedia records rs28938472 on the minus strand: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other GSS SNPs
- rs28936396A;GCarrier of a glutathione synthetase deficiency mutationImportant
- rs75863437A;GCarrier of a glutathione synthetase deficiency mutationImportant
- rs121909307C;TCarrier of a glutathione synthetase deficiency mutationImportant
- rs121909308A;GCarrier of a glutathione synthetase deficiency mutationImportant
- rs121909309A;GCarrier of a glutathione synthetase deficiency mutationImportant
Notes
From SNPedia
Notes
C;T
Unaffected in absence of a second mutation in the GSS gene; see text and links via main-rs-page
Source and license
Adapted from rs28938472 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.