rs28941473
A SNP in the ASL gene on chromosome 7. Its most notable genotype is A;A: Argininosuccinate lyase deficiency
- Gene
- ASL
- Location
- Chr 766,086,751 (GRCh38)
- Highest magnitude
- 8.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableBadArgininosuccinate lyase deficiency
- A;GBadUnaffected carrier of one bad argininosuccinate lyase allele
- G;GGoodcommon in clinvar
On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other ASL SNPs
- rs28940286T;TArgininosuccinate lyase deficiencyVery important
- rs28940287T;TArgininosuccinate lyase deficiencyVery important
- rs28940585T;TArgininosuccinate lyase deficiencyVery important
- rs28941472G;GArgininosuccinate lyase deficiencyVery important
- rs138310841T;TArgininosuccinate lyase deficiencyVery important
- rs142637046A;AArgininosuccinate lyase deficiencyVery important
- rs143793815T;TArgininosuccinate lyase deficiencyVery important
- rs145138923A;AArgininosuccinate lyase deficiencyVery important
Notes
From SNPedia
Notes
c.532G>A, p.Val178Met or V178M
A;A
see discussion at Argininosuccinate lyase deficiency
A;G
see discussion at Argininosuccinate lyase deficiency
Source and license
Adapted from rs28941473 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.