rs28941769
A SNP in the TCOF1 gene on chromosome 5. Its most notable genotype is A;G: Treacher Collins syndrome, type 1 (predicted)
- Gene
- TCOF1
- Location
- Chr 5150,361,196 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AGoodcommon in clinvar
- A;GMost notableBadTreacher Collins syndrome, type 1 (predicted)
On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other TCOF1 SNPs
- rs119470016C;TTreacher Collins syndrome, type 1 (predicted)Very important
- rs119470017C;TTreacher Collins syndrome, type 1 (predicted)Very important
- rs587776580-;ATreacher Collins syndrome, type 1 (predicted)Very important
- rs587776581-;ATACTreacher Collins syndrome, type 1 (predicted)Very important
- rs587776582-;AAGAATreacher Collins syndrome, type 1 (predicted)Very important
- rs587776583-;AGTreacher Collins syndrome, type 1 (predicted)Very important
- rs587776584-;AAGGTGAGTGGGACTGCCTreacher Collins syndrome, type 1 (predicted)Very important
- rs587776585-;ATreacher Collins syndrome, type 1 (predicted)Very important
Notes
From SNPedia
Notes
A;G
See discussion at Treacher Collins syndrome and via main SNP page
Source and license
Adapted from rs28941769 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.