rs28941774

A SNP in the UROS gene on chromosome 10. Its most notable genotype is A;A: Porphyria

Gene
UROS
Location
Chr 10125,815,081 (GRCh38)
Highest magnitude
3.5Important
Tested on
23andMe, AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. A;GBadPorphyria carrierImportant · 3.0
  3. A;AMost notableBadPorphyriaImportant · 3.5

SNPedia records rs28941774 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other UROS SNPs

All UROS SNPs

Source and license

Adapted from rs28941774 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.