rs31489(A;C)

1.75-fold reduced risk of developing lung cancer

Magnitude
2.0Worth knowing
Repute
Good
Frequency
40%Average of 11 populations
On SNPedia
rs31489(A;C)
Gene
CLPTM1L

Frequency

Share of people with A;C in each HapMap population.

  • Tuscan58%
  • Yoruba (Nigeria)50%
  • African ancestry (Southwest US)49%
  • Luhya (Kenya)49%
  • European ancestry (Utah)46%
  • Maasai (Kenya)45%
  • Mexican ancestry (Los Angeles)38%
  • Gujarati Indian30%
  • Han Chinese (Beijing)28%
  • Chinese (Denver)28%
  • Japanese (Tokyo)22%

Other genotypes of rs31489

  1. A;ANot ratedReduced lung cancer risk?Minor · 1.111% of people
  2. C;CBadIncreased risk for lung cancer and emphysemaWorth knowing · 2.049% of people

All about rs31489

Notes

From SNPedia

The frequency of the minor allele A of rs31489 was 32.49% in cancer patients versus 45.79% in disease-free subjects. Subjects carrying one copy of minor allele A are at 1.75-fold reduced risk of developing lung cancer.

Source and license

Adapted from rs31489(A;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.