rs33980500

A SNP in the TRAF3IP2 gene on chromosome 6. Its most notable genotype is T;T: 1.6x increase in risk for psoriatic arthritis

Gene
TRAF3IP2
Location
Chr 6111,592,059 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
8%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon on affy axiom dataTypical · 0.0
  2. C;TBad1.6x increase in risk for psoriatic arthritisMinor · 1.6
  3. T;TMost notableBad1.6x increase in risk for psoriatic arthritisWorth knowing · 2.0

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other TRAF3IP2 SNPs

All TRAF3IP2 SNPs

Notes

From SNPedia

Notes

reports rs33980500, with risk/non-risk alleles T/C, has an odds ratio of 1.6 (p=2.65e−16) for psoriatic arthritis based on a case/control study of ~2,000 patients.

Source and license

Adapted from rs33980500 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.