rs34570933

A SNP. Its most notable genotype is -;T: BRCA1 variant considered pathogenic for breast cancer

Gene
None listed
Highest magnitude
6.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;TMost notableBadBRCA1 variant considered pathogenic for breast cancerVery important · 6.0

On SNPedia: (-;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs34570933 represents three variants in the BRCA1 gene, all of which are considered pathogenic for breast cancer in ClinVar. Alternative names for these variants include the following: c.5182dupA, c.5181_5182delAA, and c.5182delA.

-;T

Considered pathogenic in ClinVar. Note: if raw data is "DI", exact mutation may be ambiguous.

Source and license

Adapted from rs34570933 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.