rs36095412

A SNP in the RNF186 gene on chromosome 1. Its most notable genotype is A;A: protective against ulcerative colitis

Gene
RNF186
Location
Chr 119,814,567 (GRCh38)
Highest magnitude
2.5Worth knowing
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodprotective against ulcerative colitisWorth knowing · 2.5
  2. A;GGoodprotective against ulcerative colitisWorth knowing · 2.5
  3. G;GNot ratednormal, non-protectiveTypical · 0.0

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other RNF186 SNPs

All RNF186 SNPs

Notes

From SNPedia

Notes

A protein truncating R179X variant in RNF186 confers protection against ulcerative colitis

Source and license

Adapted from rs36095412 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.