rs370793608

A SNP. Its most notable genotype is G;G: hereditary fructose intolerance

Gene
None listed
Highest magnitude
5.0Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;ABadMiscall in Ancestry v2c and v2d data; otherwise, hereditary fructose intoleranceMinor · 1.1
  2. A;CBadCarrier of a hereditary fructose intolerance mutationImportant · 3.0
  3. A;TBadCarrier for hereditary fructose intolerance mutationImportant · 3.0
  4. G;GMost notableBadhereditary fructose intoleranceVery important · 5.0
  5. G;TBadCarrier for hereditary fructose intolerance mutationImportant · 3.0
  6. T;TGoodcommon/normalTypical · 0.0

On SNPedia: (A;A), (A;C), (A;T), (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka c.612T>G (p.Tyr204Ter) and also c.612T>A (p.Tyr204Ter); both are pathogenic in ClinVar for hereditary fructosuria

A;A

see text and links via main rs-page

A;C

Unaffected in absence of a second ALDOB gene mutation

A;T

Unaffected in absence of a second ALDOB gene mutation

G;G

see text and links via main rs-page

G;T

Unaffected in absence of a second ALDOB gene mutation

Source and license

Adapted from rs370793608 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.