rs3736228(T;T)

Increased risk for osteoporosis

Magnitude
1.7Minor
Repute
Bad
Frequency
2%Average of 11 populations
On SNPedia
rs3736228(T;T)
Gene
LRP5

Frequency

Share of people with T;T in each HapMap population.

  • Japanese (Tokyo)5%
  • Chinese (Denver)4%
  • Han Chinese (Beijing)2%
  • European ancestry (Utah)2%
  • African ancestry (Southwest US)2%
  • Mexican ancestry (Los Angeles)2%
  • Tuscan1%
  • Maasai (Kenya)<1%
  • Yoruba (Nigeria)0%
  • Gujarati Indian0%
  • Luhya (Kenya)0%

Other genotypes of rs3736228

  1. C;CGoodnormalTypical · 0.077% of people
  2. C;TBadincreased risk for osteoporosisMinor · 1.321% of people

All about rs3736228

Notes

From SNPedia

Carried by 2% of people with European ancestry, this genotype has two copies of the higher risk variant (T), which leads to being 1.66 times as likely to develop osteoporosis as someone with no (T) variants for this SNP.

Source and license

Adapted from rs3736228(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.