rs3740051

A SNP in the SIRT1 gene on chromosome 10. Its most notable genotype is A;A.

Gene
SIRT1
Location
Chr 1067,884,201 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
13%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodNo summary available.Typical · 0.078% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 78%
  • European ancestry (Utah)A;A 92%
  • Han Chinese (Beijing)A;A 51%
  • Japanese (Tokyo)A;A 44%
  • Yoruba (Nigeria)A;A 99%
  • African ancestry (Southwest US)A;A 95%
  • Chinese (Denver)A;A 53%
  • Gujarati IndianA;A 68%
  • Luhya (Kenya)A;A 99%
  • Mexican ancestry (Los Angeles)A;A 72%
  • Maasai (Kenya)A;A 99%
  • TuscanA;A 87%

Other SIRT1 SNPs

All SIRT1 SNPs

Source and license

Adapted from rs3740051 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.