rs3750861

A SNP in the KLF6 gene on chromosome 10. Its most notable genotype is C;C: common in complete genomics

Gene
KLF6
Location
Chr 103,782,241 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
6%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.089% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 89%
  • European ancestry (Utah)C;C 88%
  • Han Chinese (Beijing)C;C 88%
  • Japanese (Tokyo)C;C 94%
  • Yoruba (Nigeria)C;C 98%
  • African ancestry (Southwest US)C;C 91%
  • Chinese (Denver)C;C 91%
  • Gujarati IndianC;C 78%
  • Luhya (Kenya)C;C 96%
  • Mexican ancestry (Los Angeles)C;C 78%
  • Maasai (Kenya)C;C 94%
  • TuscanC;C 83%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs10508266 and rs3750861 shows significant association with lung cancer risk rs3750861 affects expression of KLF6 splicing variants in prostate cancer and we found that its rare allele is associated with reduced lung cancer risk

Source and license

Adapted from rs3750861 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.