rs3758549(G;G)

Increased risk of parkinson's disease

Magnitude
1.1Minor
Repute
Bad
Frequency
79%Average of 11 populations
On SNPedia
rs3758549(C;C)Minus strand
Gene
GBF1

Frequency

Share of people with G;G in each HapMap population.

  • Yoruba (Nigeria)97%
  • Luhya (Kenya)91%
  • Gujarati Indian90%
  • Maasai (Kenya)85%
  • Japanese (Tokyo)81%
  • African ancestry (Southwest US)77%
  • Chinese (Denver)74%
  • Han Chinese (Beijing)72%
  • Mexican ancestry (Los Angeles)69%
  • Tuscan66%
  • European ancestry (Utah)62%

Other genotypes of rs3758549

  1. A;GNot ratednormal risk of parkinson's diseaseTypical · 0.020% of people
  2. A;ANot ratednormal risk of parkinson's diseaseTypical · 0.01% of people

All about rs3758549

Notes

From SNPedia

While this does indicate increased risk of in one Parkinson's disease study. It is so common that it makes more sense to think of the other 2 genotypes as rare risk reducers.

Source and license

Adapted from rs3758549(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.