rs3760511

A SNP in the HNF1B gene on chromosome 17. Its most notable genotype is C;C.

Gene
HNF1B
Location
Chr 1737,746,322 (GRCh38)
Highest magnitude
1.2Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
38%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TNot ratednormal risk for prostate cancerTypical · 0.044% of people
  2. G;TBad1.16x increased risk for prostate cancerTypical · 0.037% of people
  3. G;GBad1.16x increased risk for prostate cancerTypical · 0.018% of people
  4. C;CMost notableNot ratedNo summary available.Minor · 1.20% of people

SNPedia records rs3760511 on the minus strand: (A;A), (A;C), (C;C), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 44% G;T 37% G;G 18% C;C 0%
  • European ancestry (Utah)T;T 50% G;T 44% G;G 5% C;C 0%
  • Han Chinese (Beijing)T;T 11% G;T 43% G;G 46% C;C 0%
  • Japanese (Tokyo)T;T 18% G;T 57% G;G 26% C;C 0%
  • Yoruba (Nigeria)T;T 77% G;T 21% G;G 2% C;C 0%
  • African ancestry (Southwest US)T;T 70% G;T 26% G;G 4% C;C 0%
  • Chinese (Denver)T;T 14% G;T 36% G;G 51% C;C 0%
  • Gujarati IndianT;T 25% G;T 46% G;G 30% C;C 0%
  • Luhya (Kenya)T;T 76% G;T 21% G;G 3% C;C 0%
  • Mexican ancestry (Los Angeles)T;T 26% G;T 47% G;G 28% C;C 0%
  • Maasai (Kenya)T;T 69% G;T 30% G;G <1% C;C 0%
  • TuscanT;T 51% G;T 42% G;G 7% C;C 0%

Other HNF1B SNPs

All HNF1B SNPs

Notes

From SNPedia

Notes

rs3760511 increases susceptibility to Prostate cancer 1.16 times for carriers of the C allele

Source and license

Adapted from rs3760511 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.