rs7501939

A SNP in the HNF1B gene on chromosome 17. Its most notable genotype is C;T.

Gene
HNF1B
Location
Chr 1737,741,165 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
39%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TMost notableNot ratedNo summary available.Typical · 0.046% of people

On SNPedia: (T;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 46%
  • European ancestry (Utah)C;T 57%
  • Han Chinese (Beijing)C;T 36%
  • Japanese (Tokyo)C;T 47%
  • Yoruba (Nigeria)C;T 53%
  • African ancestry (Southwest US)C;T 54%
  • Chinese (Denver)C;T 29%
  • Gujarati IndianC;T 42%
  • Luhya (Kenya)C;T 47%
  • Mexican ancestry (Los Angeles)C;T 48%
  • Maasai (Kenya)C;T 44%
  • TuscanC;T 45%

Conditions, medicines and genes

Other HNF1B SNPs

All HNF1B SNPs

Notes

From SNPedia

Notes

cancerpage.com related to Prostate cancer and Type-2 diabetes The increased risk associated with rs7501939 and the closely linked rs4430796 is approximately doubled in individuals hereditarily predisposed to develop early-onset prostate cancer, based on a study of ~1,000 men. rs7501939 identified as one of three HNF1B gene SNPs associated with decreased risk for prostate cancer in two large prospective studies cancer-genetics these SNPs influence genetic risk for prostate cancer *the haplotype rs6983267 rs1016343 rs4242384 *rs7501939 *rs1859962 *rs2660753 *rs9364554 *rs6465657 *rs10993994 *rs7931342 *rs2735839 *rs5945619 *rs10993994

Source and license

Adapted from rs7501939 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.