rs376128990
A SNP in the MMAB gene on chromosome 12. Its most notable genotype is A;G: Carrier of a methylmalonic aciduria type cblB mutation
- Gene
- MMAB
- Location
- Chr 12109,561,053 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;GMost notableBadCarrier of a methylmalonic aciduria type cblB mutation
- G;GGoodcommon in clinvar
On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other MMAB SNPs
- rs28941784A;GCarrier of a methylmalonic aciduria type cblB mutationImportant
- rs199971687C;TCarrier of a methylmalonic aciduria type cblB mutationImportant
- rs369296618A;GCarrier of a methylmalonic aciduria type cblB mutationImportant
- rs398124434A;GCarrier of a methylmalonic aciduria type cblB mutationImportant
- rs746219370C;TCarrier of a methylmalonic aciduria type cblB mutationImportant
- rs756195708C;TCarrier of a methylmalonic aciduria type cblB mutationImportant
- rs763935916A;CCarrier of a methylmalonic aciduria type cblB mutationImportant
- rs864309509A;GCarrier of a methylmalonic aciduria type cblB mutationImportant
Notes
From SNPedia
Notes
A;G
Unaffected in absence of a second MMAB gene mutation
Source and license
Adapted from rs376128990 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.