rs3768716

A SNP in the BARD1 gene on chromosome 2. Its most notable genotype is T;T: normal

Gene
BARD1
Location
Chr 2214,771,070 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
14%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableNot ratednormalTypical · 0.075% of people
  2. C;TBad1.7x higher risk of aggressive neuroblastomaTypical · 0.023% of people
  3. C;CNot rated2.8x higher risk of aggressive neuroblastomaTypical · 0.02% of people

SNPedia records rs3768716 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 75% C;T 23% C;C 2%
  • European ancestry (Utah)T;T 58% C;T 36% C;C 6%
  • Han Chinese (Beijing)T;T 74% C;T 23% C;C 4%
  • Japanese (Tokyo)T;T 58% C;T 41% C;C <1%
  • Yoruba (Nigeria)T;T 96% C;T 4% C;C 0%
  • African ancestry (Southwest US)T;T 86% C;T 14% C;C 0%
  • Chinese (Denver)T;T 73% C;T 27% C;C <1%
  • Gujarati IndianT;T 56% C;T 36% C;C 8%
  • Luhya (Kenya)T;T 99% C;T <1% C;C 0%
  • Mexican ancestry (Los Angeles)T;T 55% C;T 41% C;C 3%
  • Maasai (Kenya)T;T 97% C;T 3% C;C 0%
  • TuscanT;T 70% C;T 28% C;C 3%

Conditions, medicines and genes

Other BARD1 SNPs

All BARD1 SNPs

Notes

From SNPedia

Notes

23andMe blog Each copy of a G at this SNP increases the odds of aggressive neuroblastoma by 1.68 times. allelic odds ratio of 1.68 (p = 2.74 x 10(-16)) Chromosome 6p22 locus associated with clinically aggressive neuroblastoma.

Source and license

Adapted from rs3768716 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.