rs3769823

A SNP in the CASP8 gene on chromosome 2. Its most notable genotype is A;A: common in clinvar

Gene
CASP8
Location
Chr 2201,258,272 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in clinvarTypical · 0.012% of people

SNPedia records rs3769823 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 12%
  • European ancestry (Utah)A;A 13%
  • Han Chinese (Beijing)A;A 10%
  • Japanese (Tokyo)A;A 8%
  • Yoruba (Nigeria)A;A 12%
  • African ancestry (Southwest US)A;A 13%
  • Chinese (Denver)A;A 8%
  • Gujarati IndianA;A 8%
  • Luhya (Kenya)A;A 16%
  • Mexican ancestry (Los Angeles)A;A 5%
  • Maasai (Kenya)A;A 23%
  • TuscanA;A 13%

Other CASP8 SNPs

All CASP8 SNPs

Source and license

Adapted from rs3769823 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.