rs3780374(A;A)

Substantially increased odds of developing V617F-positive MPN.

Magnitude
2.8Worth knowing
Repute
Bad
Frequency
5%Average of 11 populations
On SNPedia
rs3780374(A;A)
Gene
JAK2

Frequency

Share of people with A;A in each HapMap population.

  • Mexican ancestry (Los Angeles)10%
  • European ancestry (Utah)9%
  • Han Chinese (Beijing)7%
  • Japanese (Tokyo)6%
  • Gujarati Indian6%
  • Tuscan6%
  • Chinese (Denver)4%
  • Luhya (Kenya)4%
  • Maasai (Kenya)3%
  • Yoruba (Nigeria)0%
  • African ancestry (Southwest US)0%

Other genotypes of rs3780374

  1. A;GBadSubstantially increased odds of developing V617F-positive MPN.Worth knowing · 2.535% of people
  2. G;GGoodNo summary available.Typical · 0.060% of people

All about rs3780374

Source and license

Adapted from rs3780374(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.