rs3780374(A;G)

Substantially increased odds of developing V617F-positive MPN.

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
35%Average of 11 populations
On SNPedia
rs3780374(A;G)
Gene
JAK2

Frequency

Share of people with A;G in each HapMap population.

  • Mexican ancestry (Los Angeles)53%
  • European ancestry (Utah)47%
  • Tuscan44%
  • Chinese (Denver)41%
  • Japanese (Tokyo)38%
  • Gujarati Indian35%
  • Han Chinese (Beijing)33%
  • Maasai (Kenya)33%
  • African ancestry (Southwest US)26%
  • Yoruba (Nigeria)22%
  • Luhya (Kenya)16%

Other genotypes of rs3780374

  1. A;AMost notableBadSubstantially increased odds of developing V617F-positive MPN.Worth knowing · 2.85% of people
  2. G;GGoodNo summary available.Typical · 0.060% of people

All about rs3780374

Source and license

Adapted from rs3780374(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.