rs3796529

A SNP in the REST gene on chromosome 4. Its most notable genotype is T;T.

Gene
REST
Location
Chr 456,931,248 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
25%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableNot ratedNo summary available.Typical · 0.08% of people
  2. C;TNot ratedNo summary available.Typical · 0.031% of people
  3. C;CGoodcommon/normalTypical · 0.061% of people

SNPedia records rs3796529 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 8% C;T 31% C;C 61%
  • European ancestry (Utah)T;T 4% C;T 25% C;C 72%
  • Han Chinese (Beijing)T;T 16% C;T 36% C;C 49%
  • Japanese (Tokyo)T;T 23% C;T 39% C;C 38%
  • Yoruba (Nigeria)T;T 7% C;T 39% C;C 54%
  • African ancestry (Southwest US)T;T 2% C;T 35% C;C 64%
  • Chinese (Denver)T;T 15% C;T 39% C;C 45%
  • Gujarati IndianT;T 6% C;T 36% C;C 58%
  • Luhya (Kenya)T;T 8% C;T 37% C;C 55%
  • Mexican ancestry (Los Angeles)T;T 7% C;T 24% C;C 69%
  • Maasai (Kenya)T;T <1% C;T 9% C;C 90%
  • TuscanT;T 2% C;T 24% C;C 74%

Other REST SNPs

All REST SNPs

Source and license

Adapted from rs3796529 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.