rs3825942(G;G)

Common but 10x higher glaucoma risk in most (but not all) populations

Magnitude
2.3Worth knowing
Repute
Bad
Frequency
57%Average of 11 populations
On SNPedia
rs3825942(G;G)
Gene
LOXL1

Frequency

Share of people with G;G in each HapMap population.

  • Japanese (Tokyo)77%
  • Han Chinese (Beijing)72%
  • Chinese (Denver)69%
  • European ancestry (Utah)68%
  • Tuscan63%
  • Gujarati Indian63%
  • Mexican ancestry (Los Angeles)62%
  • Maasai (Kenya)43%
  • African ancestry (Southwest US)38%
  • Yoruba (Nigeria)34%
  • Luhya (Kenya)33%

Other genotypes of rs3825942

  1. A;AMost notableGood10x to 27x lower risk of exfoliation glaucomaWorth knowing · 2.57% of people
  2. A;GGoodpossibly lower glaucoma riskMinor · 1.836% of people

All about rs3825942

Notes

From SNPedia

This genotype is found in 2 out of 3 people, but has been repeatedly linked to a much higher risk of glaucoma. However a 2010 paper in a south african population reports reduced risk, casting some doubts.

References

Source and license

Adapted from rs3825942(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.