rs386833491

A SNP in the SLC26A3 gene on chromosome 7. Its most notable genotype is -;-: Congenital secretory diarrhea (predicted)

Gene
SLC26A3
Location
Chr 7107,786,845 (GRCh38)
Highest magnitude
5.8Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;-Most notableBadCongenital secretory diarrhea (predicted)Very important · 5.8
  2. -;GGTBadCarrier for a congenital secretory diarrhea mutationImportant · 3.0
  3. GGT;GGTGoodcommon in clinvarTypical · 0.0

On SNPedia: (-;-), (-;GGT), (GGT;GGT). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

aka c.951_953delGGT (p.Val318del)

-;-

See links via main rs-page.

-;GGT

Unaffected in absence of a second SLC26A3 gene mutation; see links via main rs-page.

Source and license

Adapted from rs386833491 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.