rs386833883

A SNP in the NPHS1 gene on chromosome 19. Its most notable genotype is -;G: Carrier of a Finnish congenital nephrotic syndrome (NPHS1) mutation

Gene
NPHS1
Location
Chr 1935,846,154 (GRCh38)
Highest magnitude
3.0Important
Tested on
Not on consumer chips

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. -;GMost notableBadCarrier of a Finnish congenital nephrotic syndrome (NPHS1) mutationImportant · 3.0
  2. G;GGoodcommon in clinvarTypical · 0.0

SNPedia records rs386833883 on the minus strand: (-;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other NPHS1 SNPs

All NPHS1 SNPs

Notes

From SNPedia

Notes

aka c.1481delC (p.Ser494Cysfs)

-;G

Unaffected in absence of a second NPHS1 gene mutation

Source and license

Adapted from rs386833883 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.