rs387907571
A SNP in the DNAJC13 gene on chromosome 3. Its most notable genotype is A;G: Parkinson's disease, possible
- Gene
- DNAJC13
- Location
- Chr 3132,477,995 (GRCh38)
- Highest magnitude
- 6.0Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
rs387907571, also known as Asn855Ser, represents a rare mutation occurring in exon 24 of the DNAJC13 gene on chromosome 3. The rs387907571(G) allele has been reported to be a causative mutation for autosomal dominant Parkinson's disease, found primarily in patients with Dutch-German-Russian Mennonite heritage. A subsequent study of almost 2,000 Caucasian Parkinson's patients did not reveal this mutation (or any other in exon 24 of this gene), so rs387907571 is not a common cause of Parkinson's disease.
A;G
The rare (G) allele for this mutation is reported to be an autosomal dominant mutation causing Parkinson's disease. See discussion at rs387907571.
Source and license
Adapted from rs387907571 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.