rs397514442

A SNP in the HSD3B7 gene on chromosome 16. Its most notable genotype is -;CT: Likely miscall in Ancestry v2c data; otherwise, carrier of a bile acid synthesis defect mutation

Gene
HSD3B7
Location
Chr 1630,988,112 (GRCh38)
Highest magnitude
3.0Important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;CTMost notableBadLikely miscall in Ancestry v2c data; otherwise, carrier of a bile acid synthesis defect mutationImportant · 3.0
  2. CT;CTGoodcommon in clinvarTypical · 0.0

On SNPedia: (-;CT), (CT;CT). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other HSD3B7 SNPs

All HSD3B7 SNPs

Notes

From SNPedia

Notes

c.1039_1040delCT (p.Leu347Valfs)

-;CT

Unaffected in absence of a second mutation in the HSD3B7 gene; see links via main rs-page.

Source and license

Adapted from rs397514442 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.