rs397514767

A SNP in the CD59 gene on chromosome 11. Its most notable genotype is T;T: inherited CD59 deficiency

Gene
CD59
Location
Chr 1133,710,247 (GRCh38)
Highest magnitude
7.0Very important
Tested on
Not on consumer chips

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableBadinherited CD59 deficiencyVery important · 7.0
  2. C;TBadunaffected carrier of an inherited CD59 deficiency alleleVery important · 4.0
  3. C;CGoodcommon in clinvarTypical · 0.0

SNPedia records rs397514767 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other CD59 SNPs

All CD59 SNPs

Notes

From SNPedia

Notes

rs397514767 is a SNP in the CD59 gene on chromosome 11; aka c.266G>A, p.Cys89Tyr or C89Y. A G>A change, when present in two copies, leads to an inherited CD59 deficiency including hemolytic anemia and immune-mediated polyneuropathy. See also OMIM 107271.0002

T;T

see discussion at rs397514767

C;T

see discussion at rs397514767

Source and license

Adapted from rs397514767 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.