rs397515330

A SNP in the PRKG1 gene on chromosome 10. Its most notable genotype is A;G: Familial thoracic aortic aneurysms and dissections (FTAAD)

Gene
PRKG1
Location
Chr 1051,467,819 (GRCh38)
Highest magnitude
6.5Very important
Tested on
23andMe, AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;GMost notableBadFamilial thoracic aortic aneurysms and dissections (FTAAD)Very important · 6.5
  2. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other PRKG1 SNPs

All PRKG1 SNPs

Notes

From SNPedia

Notes

aka c.575G>A (p.Arg192Gln)

Source and license

Adapted from rs397515330 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.