rs397515363
A SNP in the DNAI1 gene on chromosome 9. Its most notable genotype is T;T: Primary ciliary dyskinesia
- Gene
- DNAI1
- Location
- Chr 934,459,055 (GRCh38)
- Highest magnitude
- 5.5Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Goodcommon in clinvar
- -;TBadCarrier of a primary ciliary dyskinesia mutation
- T;TMost notableBadPrimary ciliary dyskinesia
On SNPedia: (-;-), (-;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other DNAI1 SNPs
- rs79833450A;GCarrier of a primary ciliary dyskinesia mutationImportant
- rs200669099A;GCarrier of a primary ciliary dyskinesia mutationImportant
- rs376252276A;GCarrier of a primary ciliary dyskinesia mutationImportant
- rs397515563A;GCarrier of a primary ciliary dyskinesia mutationImportant
- rs606231164-;AATACarrier of a primary ciliary dyskinesia mutationImportant
- rs606231165-;CCAAGGTCTTCACarrier of a primary ciliary dyskinesia mutationImportant
- rs769284314A;GCarrier of a primary ciliary dyskinesia mutationImportant
- rs876657683-;CCarrier of a primary ciliary dyskinesia mutationImportant
Notes
From SNPedia
Notes
aka c.48+2dupT (p.Ser17ValfsTer12) This SNP may represent the most common DNAI1 gene mutation associated with primary ciliary dyskinesia.
-;T
Unaffected in absence of a second DNAI1 gene mutation; see links via main rs-page.
T;T
See links via main rs-page
Source and license
Adapted from rs397515363 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.