rs398123156

A SNP in the EMD gene on chromosome X. Its most notable genotype is -;-: Emery-Dreifuss Muscular Dystrophy

Gene
EMD
Location
Chr X154,380,252 (GRCh38)
Highest magnitude
6.4Very important
Tested on
23andMe, AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;-Most notableBadEmery-Dreifuss Muscular DystrophyVery important · 6.4
  2. -;ATGAAGAGAGCTACTBadCarrier of an Emery-Dreifuss Muscular Dystrophy mutationImportant · 3.0
  3. ATGAAGAGAGCTACT;ATGAAGAGAGCTACTGoodcommon in clinvarTypical · 0.0
  4. CTACTATGAAGAGAG;CTACTATGAAGAGAGGoodcommon in clinvarTypical · 0.0
  5. I;IGoodcommon genotypeTypical · 0.0

On SNPedia: (-;-), (-;ATGAAGAGAGCTACT), (ATGAAGAGAGCTACT;ATGAAGAGAGCTACT), (CTACTATGAAGAGAG;CTACTATGAAGAGAG), (I;I). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other EMD SNPs

All EMD SNPs

Notes

From SNPedia

Notes

-;ATGAAGAGAGCTACT

X-linked recessive, however, females may have some risk for cardiac and muscle problems

Source and license

Adapted from rs398123156 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.