rs398124641
A SNP in the SLC52A2 gene on chromosome 8. Its most notable genotype is A;A: Brown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommended
- Gene
- SLC52A2
- Location
- Chr 8144,360,408 (GRCh38)
- Highest magnitude
- 8.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableBadBrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommended
- A;GBadCarrier of a Brown-Vialetto-Van Laere syndrome type 2 mutation
- G;GGoodcommon in clinvar
On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other SLC52A2 SNPs
- rs148234606C;CBrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
- rs368924997A;ABrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
- rs374071862T;TBrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
- rs375088539T;TBrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
- rs397514538C;CBrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
- rs397514657T;TBrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
- rs397514658A;ABrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
- rs398123067A;ABrown-Vialetto-Van Laere syndrome type 2 mutation; riboflavin treatment recommendedVery important
Notes
From SNPedia
Notes
A;A
See discussion at Brown-Vialetto-Van laere syndrome, including recommendation for immediate riboflavin supplementation.
A;G
Unaffected carrier in absence of second mutation; see discussion at Brown-Vialetto-Van laere syndrome.
Source and license
Adapted from rs398124641 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.