rs4523540
A SNP in the TNNT2 gene on chromosome 1. Its most notable genotype is T;T: common in clinvar
- Gene
- TNNT2
- Location
- Chr 1201,359,639 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 6 HapMap populations.
- AverageT;T 93%
- European ancestry (Utah)T;T 100%
- Han Chinese (Beijing)T;T 100%
- Japanese (Tokyo)T;T 100%
- Yoruba (Nigeria)T;T 100%
- Maasai (Kenya)T;T 59%
- TuscanT;T 99%
Related
Other TNNT2 SNPs
- rs74315379C;THypertrophic CardiomyopathyVery important
- rs121964856A;GHypertrophic CardiomyopathyVery important
- rs45525839C;GDilated cardiomyopathyVery important
- rs111377893A;CFamilial Hypertrophic CardiomyopathyVery important
- rs121964858A;TFamilial Hypertrophic CardiomyopathyVery important
- rs376923877G;TFamilial Hypertrophic CardiomyopathyVery important
- rs397516454A;CDilated cardiomyopathyVery important
- rs397516456A;GFamilial Hypertrophic CardiomyopathyVery important
Source and license
Adapted from rs4523540 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.