rs4525

A SNP in the F5 gene on chromosome 1. Its most notable genotype is T;T: common in clinvar

Gene
F5
Location
Chr 1169,542,496 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
24%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in clinvarTypical · 0.057% of people
  2. C;TNot ratedNo summary available.Typical · 0.037% of people
  3. C;CNot ratedNo summary available.Typical · 0.06% of people

SNPedia records rs4525 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 57% C;T 37% C;C 6%
  • European ancestry (Utah)T;T 55% C;T 38% C;C 7%
  • Han Chinese (Beijing)T;T 67% C;T 31% C;C 2%
  • Japanese (Tokyo)T;T 64% C;T 32% C;C 4%
  • Yoruba (Nigeria)T;T 69% C;T 30% C;C 2%
  • African ancestry (Southwest US)T;T 53% C;T 40% C;C 7%
  • Chinese (Denver)T;T 59% C;T 36% C;C 5%
  • Gujarati IndianT;T 39% C;T 55% C;C 7%
  • Luhya (Kenya)T;T 66% C;T 32% C;C 2%
  • Mexican ancestry (Los Angeles)T;T 41% C;T 35% C;C 24%
  • Maasai (Kenya)T;T 53% C;T 42% C;C 5%
  • TuscanT;T 58% C;T 36% C;C 6%

Other F5 SNPs

All F5 SNPs

Source and license

Adapted from rs4525 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.