rs4536

A SNP in the CYP11B2 gene on chromosome 8. Its most notable genotype is C;C: common in clinvar

Gene
CYP11B2
Location
Chr 8142,914,345 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
16%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in clinvarTypical · 0.081% of people

SNPedia records rs4536 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 81%
  • European ancestry (Utah)C;C 94%
  • Han Chinese (Beijing)C;C 89%
  • Japanese (Tokyo)C;C 89%
  • Yoruba (Nigeria)C;C 52%

Other CYP11B2 SNPs

All CYP11B2 SNPs

Source and license

Adapted from rs4536 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.