rs460000(G;G)
Better response to amphetamine
- Magnitude
- 2.0Worth knowing
- Repute
- Not rated
- Frequency
- 33%Average of 11 populations
- On SNPedia
- rs460000(C;C)Minus strand
- Gene
- SLC6A3
Frequency
Share of people with G;G in each HapMap population.
- Tuscan60%
- European ancestry (Utah)57%
- Maasai (Kenya)49%
- Mexican ancestry (Los Angeles)41%
- African ancestry (Southwest US)30%
- Gujarati Indian29%
- Yoruba (Nigeria)25%
- Luhya (Kenya)20%
- Chinese (Denver)19%
- Han Chinese (Beijing)19%
- Japanese (Tokyo)14%
Other genotypes of rs460000
Notes
From SNPedia
Individuals with the C/C genotype at rs460000 (N = 83) reported approximately twofold higher ratings of stimulation and euphoria relative to the A/A+A/C (N = 69) genotype group, at both the 10 and 20 mg doses. PMID 20091113
References
Source and license
Adapted from rs460000(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.