rs4648317(A;G)

Prone to higher nicotine dependence?

Magnitude
0.0Typical
Repute
Not rated
Frequency
34%Average of 11 populations
On SNPedia
rs4648317(C;T)Minus strand
Gene
DRD2

Frequency

Share of people with A;G in each HapMap population.

  • Chinese (Denver)53%
  • Mexican ancestry (Los Angeles)50%
  • Japanese (Tokyo)47%
  • Han Chinese (Beijing)43%
  • Gujarati Indian34%
  • Maasai (Kenya)32%
  • Yoruba (Nigeria)25%
  • Tuscan24%
  • European ancestry (Utah)23%
  • African ancestry (Southwest US)21%
  • Luhya (Kenya)19%

Other genotypes of rs4648317

  1. G;GGoodnormalTypical · 0.059% of people
  2. A;AMost notableBadprone to higher nicotine dependence, more impulsive/sensation seekingMinor · 1.27% of people

All about rs4648317

Source and license

Adapted from rs4648317(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.