rs4680(A;G)

Intermediate dopamine levels, other effects

Magnitude
0.0Typical
Repute
Not rated
Frequency
42%Average of 11 populations
On SNPedia
rs4680(A;G)
Gene
COMT

Frequency

Share of people with A;G in each HapMap population.

  • Tuscan51%
  • European ancestry (Utah)46%
  • Japanese (Tokyo)46%
  • Mexican ancestry (Los Angeles)45%
  • Chinese (Denver)44%
  • Gujarati Indian43%
  • Yoruba (Nigeria)42%
  • Luhya (Kenya)42%
  • Maasai (Kenya)37%
  • Han Chinese (Beijing)37%
  • African ancestry (Southwest US)30%

Other genotypes of rs4680

  1. A;AMost notableGood(worrier) advantage in memory and attention tasksWorth knowing · 2.513% of people
  2. G;GGood(warrior) multiple associations, see detailsWorth knowing · 2.545% of people

All about rs4680

Notes

From SNPedia

As is often the case with heterozygotes, shares many traits intermediately between the (A;A) and (G;G) homozygotes. Specific (A;G) findings include:

Source and license

Adapted from rs4680(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.