rs4770433
A SNP in the SACS gene on chromosome 13. Its most notable genotype is A;A: common in clinvar
- Gene
- SACS
- Location
- Chr 1323,329,652 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 35%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 49%
- European ancestry (Utah)A;A 31%
- Han Chinese (Beijing)A;A 45%
- Japanese (Tokyo)A;A 27%
- Yoruba (Nigeria)A;A 68%
- African ancestry (Southwest US)A;A 63%
- Chinese (Denver)A;A 39%
- Gujarati IndianA;A 36%
- Luhya (Kenya)A;A 83%
- Mexican ancestry (Los Angeles)A;A 41%
- Maasai (Kenya)A;A 72%
- TuscanA;A 35%
Related
Other SACS SNPs
- rs137853016G;Gneurodegenerative disorder (ARSACS)Very important
- rs137853017G;Gneurodegenerative disorder (ARSACS)Very important
- rs137853018G;Gneurodegenerative disorder (ARSACS)Very important
- rs137853019G;Gneurodegenerative disorder (ARSACS)Very important
- rs281865117-;-neurodegenerative disorder (ARSACS)Very important
- rs281865118A;Aneurodegenerative disorder (ARSACS)Very important
- rs606231163G;Gneurodegenerative disorder (ARSACS)Very important
- rs2031640A;Acommon on affy axiom dataTypical
Notes
From SNPedia
Notes
Interleukin 12 (IL12) protein levels
Source and license
Adapted from rs4770433 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.