rs4819756

A SNP in the PRODH gene on chromosome 22. Its most notable genotype is A;G.

Gene
PRODH
Location
Chr 2218,925,165 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
26%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;GMost notableNot ratedNo summary available.Typical · 0.025% of people

On SNPedia: (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;G 25%
  • European ancestry (Utah)A;G 54%
  • Han Chinese (Beijing)A;G 7%
  • Japanese (Tokyo)A;G 5%
  • Yoruba (Nigeria)A;G 5%
  • African ancestry (Southwest US)A;G 23%
  • Chinese (Denver)A;G 8%
  • Gujarati IndianA;G 44%
  • Luhya (Kenya)A;G 13%
  • Mexican ancestry (Los Angeles)A;G 48%
  • Maasai (Kenya)A;G 25%
  • TuscanA;G 47%

Conditions, medicines and genes

Other PRODH SNPs

All PRODH SNPs

Notes

From SNPedia

Notes

plos () - The minor alleles of rs4819756 and rs2870983 were significantly negatively associated with schizophrenia

Source and license

Adapted from rs4819756 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.