rs4917

A SNP in the AHSG gene on chromosome 3. Its most notable genotype is C;T.

Gene
AHSG
Location
Chr 3186,619,924 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
29%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TMost notableNot ratedNo summary available.Typical · 0.037% of people

On SNPedia: (T;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 37%
  • European ancestry (Utah)C;T 38%
  • Han Chinese (Beijing)C;T 40%
  • Japanese (Tokyo)C;T 37%
  • Yoruba (Nigeria)C;T 44%
  • African ancestry (Southwest US)C;T 39%
  • Chinese (Denver)C;T 41%
  • Gujarati IndianC;T 24%
  • Luhya (Kenya)C;T 30%
  • Mexican ancestry (Los Angeles)C;T 52%
  • Maasai (Kenya)C;T 20%
  • TuscanC;T 39%

Conditions, medicines and genes

Other AHSG SNPs

All AHSG SNPs

Notes

From SNPedia

Notes

rs4917 is thought to regulate body fat levels and insulin sensitivity. see obesity link1 the MET/MET genotype has been previously linked with reduced plasma lipid levels and lower body fat concentrations. link2 Homozygosity for the rs2593813:G-rs4917:Met-rs4918:Ser haplotype conferred an increased risk for leanness (odds ratio=1.90, P=0.027).

Source and license

Adapted from rs4917 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.