rs4988321(A;G)

Very slightly increased risk for osteoporosis

Magnitude
1.1Minor
Repute
Bad
Frequency
2%Average of 4 populations
On SNPedia
rs4988321(A;G)
Gene
LRP5

Frequency

Share of people with A;G in each HapMap population.

  • European ancestry (Utah)7%
  • Han Chinese (Beijing)0%
  • Japanese (Tokyo)0%
  • Yoruba (Nigeria)0%

Other genotypes of rs4988321

  1. A;AMost notableBadslightly increased (~1.3x) risk for osteoporosisMinor · 1.30% of people
  2. G;GGoodnormalTypical · 0.098% of people

All about rs4988321

Source and license

Adapted from rs4988321(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.