rs5068
A SNP in the NPPA-AS1 gene on chromosome 1. Its most notable genotype is A;A.
- Gene
- NPPA-AS1
- Location
- Chr 111,845,917 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 3%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs5068 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageA;A 94%
- European ancestry (Utah)A;A 87%
- Han Chinese (Beijing)A;A 100%
- Japanese (Tokyo)A;A 100%
- Yoruba (Nigeria)A;A 95%
- African ancestry (Southwest US)A;A 98%
- Gujarati IndianA;A 93%
- Luhya (Kenya)A;A 94%
- Maasai (Kenya)A;A 86%
- TuscanA;A 91%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
A study of ~15,000 Europeans found that increased circulating natriuretic peptide and thus lower blood pressure and hypertension were associated with SNPs rs17376328(A), rs5068, rs198358(C), rs632793(G) 23andMe blog
Source and license
Adapted from rs5068 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.