rs5326

A SNP in the DRD1 gene on chromosome 5. Its most notable genotype is C;T: possible psychiatric risks

Gene
DRD1
Location
Chr 5175,443,193 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
17%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableBadpossible psychiatric risksMinor · 1.030% of people

SNPedia records rs5326 on the minus strand: (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 30%
  • European ancestry (Utah)C;T 25%
  • Han Chinese (Beijing)C;T 40%
  • Japanese (Tokyo)C;T 47%
  • Yoruba (Nigeria)C;T 26%
  • African ancestry (Southwest US)C;T 28%
  • Chinese (Denver)C;T 36%
  • Gujarati IndianC;T 26%
  • Luhya (Kenya)C;T 26%
  • Mexican ancestry (Los Angeles)C;T 22%
  • Maasai (Kenya)C;T 35%
  • TuscanC;T 19%

Other DRD1 SNPs

All DRD1 SNPs

Notes

From SNPedia

Notes

No genetic association between dopamine D1 receptor gene and (early onset) schizophrenia.

Source and license

Adapted from rs5326 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.