rs556450190

A SNP in the AP4E1 gene on chromosome 15. Its most notable genotype is A;A: possible association with stuttering

Gene
AP4E1
Location
Chr 1550,997,380 (GRCh38)
Highest magnitude
2.9Worth knowing
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadpossible association with stutteringWorth knowing · 2.9
  2. A;GBadpossible association with stutteringWorth knowing · 2.9
  3. G;GGoodcommon/normalTypical · 0.0

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other AP4E1 SNPs

All AP4E1 SNPs

Notes

From SNPedia

Notes

rs556450190, also known as c.2401G>A, p.Glu801Lys or E801K, is a variant in the AP4E1 gene on chromosome 15. The minor (A) allele of rs556450190 was reported as a mutation in the AP4E1 gene associated with stuttering in a 2015 study.

A;A

see rs556450190

A;G

see rs556450190

Source and license

Adapted from rs556450190 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.