rs560588447
A SNP in the KLKB1 gene on chromosome 4. Its most notable genotype is -;T: Carrier of a prekallikrein deficiency mutation
- Gene
- KLKB1
- Location
- Chr 4186,236,896 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- 23andMe
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Goodcommon/normal
- -;TMost notableBadCarrier of a prekallikrein deficiency mutation
On SNPedia: (-;-), (-;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Notes
From SNPedia
Notes
Prekallikrein deficiency (recessive); aka c.451dupT This SNP is included in a curated list of mutations useful to include on an Ashkenazi Jews screening panel.
-;T
Unaffected in absence of a second KLKB1 mutation; see links via main rs-page
Source and license
Adapted from rs560588447 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.