rs560887

A SNP in the G6PC2 gene on chromosome 2. Its most notable genotype is C;C: Avg. fasting Plasma Glucose 5.18 mmol/L (93 mg/dl).

Gene
G6PC2
Location
Chr 2168,906,638 (GRCh38)
Highest magnitude
2.1Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
15%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TGoodAvg. fasting Plasma Glucose 5.06 mmol/L (91 mg/dl).Worth knowing · 2.02% of people
  2. C;TBadAvg. fasting Plasma Glucose 5.12 mmol/L (92 mg/dl).Worth knowing · 2.017% of people
  3. C;CMost notableBadAvg. fasting Plasma Glucose 5.18 mmol/L (93 mg/dl).Worth knowing · 2.181% of people

SNPedia records rs560887 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageT;T 2% C;T 17% C;C 81%
  • European ancestry (Utah)T;T 10% C;T 46% C;C 45%
  • Han Chinese (Beijing)T;T 0% C;T 3% C;C 97%
  • Japanese (Tokyo)T;T 0% C;T 7% C;C 93%
  • Yoruba (Nigeria)T;T 0% C;T <1% C;C 99%
  • Chinese (Denver)T;T 0% C;T 5% C;C 95%
  • Gujarati IndianT;T 3% C;T 25% C;C 72%
  • Luhya (Kenya)T;T 0% C;T <1% C;C 99%
  • Mexican ancestry (Los Angeles)T;T 0% C;T 34% C;C 66%
  • Maasai (Kenya)T;T 0% C;T 11% C;C 89%
  • TuscanT;T 8% C;T 38% C;C 54%

Other G6PC2 SNPs

All G6PC2 SNPs

Notes

From SNPedia

Show notes, about 240 words

rs560887, p = 4 x 10(-7)) *654 normoglycemic subjects, replicated in 9,353 subjects *fasting plasma glucose (FPG) (beta = -0.06 mmol/l per A-allele, combined p = 4 x 10(-23)) and with pancreatic beta-cell function (Homa-B model, combined p = 3 x 10(-13)) in three populations; however it was not associated with type 2 diabetes risk. (ageing) Blood Glucose

T;T

Slightly lower blood glucose. Fasting Plasma Glucose is the amount of sugar in your blood when you wake up. It's required to power your body, but too much is very bad for you. Fasting plasma glucose between 5.6 mmol/L and 6.9 mmol/L (101 – 125 mg/dl) is considered pre-diabetes. Fasting plasma glucose higher than 7 mmol/L (126 mg/dl) is considered diabetes.

C;T

Slightly lower blood glucose. Fasting Plasma Glucose is the amount of sugar in your blood when you wake up. It's required to power your body, but too much is very bad for you. Fasting plasma glucose between 5.6 mmol/L and 6.9 mmol/L (101 – 125 mg/dl) is considered pre-diabetes. Fasting plasma glucose higher than 7 mmol/L (126 mg/dl) is considered diabetes.

C;C

Slightly higher blood glucose. Fasting Plasma Glucose is the amount of sugar in your blood when you wake up. It's required to power your body, but too much is very bad for you. Fasting plasma glucose between 5.6 mmol/L and 6.9 mmol/L (101 – 125 mg/dl) is considered pre-diabetes. Fasting plasma glucose higher than 7 mmol/L (126 mg/dl) is considered diabetes.

Source and license

Adapted from rs560887 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.