rs572010627
A SNP in the MPZ gene on chromosome 1. Its most notable genotype is A;T: Charcot-Marie-Tooth (CMT) disease type 1B (predicted)
- Gene
- MPZ
- Location
- Chr 1161,306,738 (GRCh38)
- Highest magnitude
- 6.2Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;TMost notableBadCharcot-Marie-Tooth (CMT) disease type 1B (predicted)
- T;TGoodcommon/normal
On SNPedia: (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other MPZ SNPs
- rs121913583C;TCharcot-Marie-Tooth Disease, type 1Very important
- rs121913584G;TCharcot-Marie-Tooth Disease, type 1Very important
- rs121913587A;GCharcot-Marie-Tooth Disease, type 1Very important
- rs121913588C;TCharcot-Marie-Tooth Disease, type 1Very important
- rs121913589C;GCharcot-Marie-Tooth Disease, type 1Very important
- rs121913590A;GCharcot-Marie-Tooth Disease, type 1Very important
- rs121913593A;GCharcot-Marie-Tooth Disease, type 1Very important
- rs121913594C;TCharcot-Marie-Tooth Disease, type 1Very important
Notes
From SNPedia
Notes
aka c.418T>A (p.Ser140Thr or S140T)
A;T
see text and links via main rs-page
Source and license
Adapted from rs572010627 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.