rs5743815
A SNP in the TLR6 gene on chromosome 4. Its most notable genotype is A;A: common in complete genomics
- Gene
- TLR6
- Location
- Chr 438,828,194 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 2%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs5743815 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 8 HapMap populations.
- AverageA;A 97%
- European ancestry (Utah)A;A 97%
- Han Chinese (Beijing)A;A 100%
- Japanese (Tokyo)A;A 100%
- Yoruba (Nigeria)A;A 100%
- African ancestry (Southwest US)A;A 97%
- Gujarati IndianA;A 98%
- Mexican ancestry (Los Angeles)A;A 88%
- TuscanA;A 99%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
rs5743815, a SNP in the TLR6 gene also known as V427A, is associated with risk for developing Non-Hodgkin Lymphoma based on a study of 458 patients. The odds ratio is 5.20 (CI: 1.77-15.3, p<0.01).
Source and license
Adapted from rs5743815 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.