rs587776528

A SNP in the PIGM gene on chromosome 1. Its most notable genotype is C;G: Carrier for a glycosylphosphatidylinositol deficiency mutation

Gene
PIGM
Location
Chr 1160,032,009 (GRCh38)
Highest magnitude
3.0Important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. C;GMost notableBadCarrier for a glycosylphosphatidylinositol deficiency mutationImportant · 3.0
  3. C;CGoodcommon in clinvarTypical · 0.0

SNPedia records rs587776528 on the minus strand: (C;C), (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

A Whole-Genome Analysis Framework for Effective Identification of Pathogenic Regulatory Variants in Mendelian Disease. This SNP maps to a position listed in Table S6 as a non-coding variant that their biocurators felt was convincingly associated with a Mendelian disease. see: OMIM 610273.0001

C;G

Unaffected in absence of a second PIGM gene mutation

Source and license

Adapted from rs587776528 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.