rs587776916

A SNP in the IFITM5 gene on chromosome 11. Its most notable genotype is C;T: Osteogenesis imperfecta type 5

Gene
IFITM5
Location
Chr 11299,504 (GRCh38)
Highest magnitude
4.9Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableBadOsteogenesis imperfecta type 5Very important · 4.9
  2. G;GGoodcommon in clinvarTypical · 0.0
  3. C;CGoodcommon in clinvarTypical · 0.0

SNPedia records rs587776916 on the minus strand: (A;G), (C;C), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka c.-14C>T This IFITM5 gene mutation, c.-14C>T, is located in the 5' UTR region of the gene and appears to account for most cases of dominantly inherited osteogenesis imperfecta, type V..

C;T

see rs587776916

Source and license

Adapted from rs587776916 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.